21 CFR 3.2(e) defines a Combination Product as one comprised of any combination of the following Constituent Parts:

• Drug and Device
• Biological Product and Device
• Drug and Biological Product
• Drug, Device and Biological Product

Some examples of combination products include:

• Pre-filled syringes
• Insulin injector pens
• Metered dose inhalers
• Transdermal patches
• Drug eluting stents
• Catheters with antimicrobial coatings
• Infusion pumps
• Medicated wound treatments
• Therapeutic orthopedic implants