Cell and Gene Therapy

Gene Therapy: Adeno-Associated Virus and Lentivirus Processing

The exciting technology of gene therapy has offered hope for patients with genetic diseases. Focusing on AAV and LVV, we’ll explore the different process steps for gene therapy manufacturing, along with the mechanisms, equipment, and challenges of this transformative medical field.

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CEU Credits: 0.1
Course Code: ELM-728
Duration: 15 mins
Skill Level: Intermediate
Language: English
Final Exam: Yes
Certification: Yes
Version: v1.0
Effective Date: 10/15/2024

Curriculum for this course

A Glimmer of Hope
What is Gene Therapy?
Gene Therapy Approaches
Viral Vectors
Addressing Gene Therapy Challenges
Process Overview
Buffer and Media Preparation
Cell Banking
Cell Expansion
Viral Vector Production
Upstream Check-In
Viral Vector Harvest With Clarification
Acidification With Clarification
Tangential Flow Filtration (TFF)
Filtration and Filling
Downstream Check-In
Promising Results
Test your Knowledge!
v1.0 - Course released on 01/28/2025

Author

Timothy Frade

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